Kalipada Pahan


Kalipada Pahan, Professor of Neurological Sciences, Biochemistry and Pharmacology, and the Floyd A. Davis, M.D., Endowed Chair of Neurology in Rush University Medical Center, is an eminent Indian American neuroscientist involved in translational research on multiple sclerosis, Parkinsons disease, Alzheimers disease, dementia, and Batten disease. He is known for his research on statins, cholesterollowering drugs. He first explored the application of statins in suppressing the inflammatory events in microglia, astroglia and macrophages. This finding has revolutionized the research on statin drugs. Later his lab has shown that statins may be beneficial in protecting neurons and improving locomotor activities in Parkinsons disease by suppressing the activation of p21Ras. Recently his lab has delineated a unique crosstalk between fat and memory in which the lipidlowering transcription factor PPARalpha controls the formation of hippocampal memory via transcriptional regulation of CREB .

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Source: Wikipedia


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